Blood coagulation analyzer test method of comparison of various medical equipment manufacturers

Blood coagulation analyzer test method of comparison of various medical equipment manufacturers at home and abroad production of semi-automatic blood coagulation instrument are based on solidification method to measure the blood clotting process. And optical and magnetic beads method, optical and magnetic beads method used for detection of coagulation, in terms of methodology, the advantages of optical method is of simple structure, high sensitivity. Ease of automation, etc. The disadvantage is vulnerable to specific plasma interference, each manufacturer has taken various measures to make up for this.

Advantages of magnetic circuit method is not affected by specific plasma interference, less dosage, faults, smooth degree of the quality of the magnetic beads, glass, etc., all can affect the measurement result. Some manufacturers to sell their products in the methodology, the slice of the one-sided emphasis on the superiority of some kind of method is unsatisfactory. One of the national production of blood clot meter two kinds of methods, and dominated by optical method, especially in the automatic blood coagulation instrument. And judge the merits of the instrument has a variety of aspects including methods, design, process, etc.

(perlong medical brand, blood coagulation analyzer PUN - 2048 - b)

Blood coagulation is a series of clotting factor chain the result of the enzyme reaction. Blood clotting factor with no active enzyme exists in the form of the original, when an activated clotting factors, can make a lot of clotting factor has been activated, in order to each other have complex catalyst, is called the "waterfall theory". The theory of "waterfall" catastrophe in blood on the biophysical characteristics of performance for resistance increase viscosity enhancement method (current) magnetic beads (method), rising turbidity method (optical). Due to the current method of measuring reliability is poor, therefore replaced by magnetic beads and optical method.
Optical method of blood coagulation instrument is according to the change of plasma coagulation process turbidity is measured in blood coagulation function. According to the different optical measuring principle of instrument, and can be divided into scattering turbidimetry and transmission turbidimetry. Magnetic beads method is based on the change of plasma viscosity in the process of solidification to measure blood coagulation function. According to the instrument for measuring principle of the magnetic particles move, and can be divided into photoelectric detection method and the magnetic beads detection method.